This includes key blocks and secret room doors, +1.0 Damage Up, but each rock tear has a random damage modifier that can go up or down (x0.5 to x2), Allows Isaac to charge by double tapping the same direction, dealing damage to any enemies caught, You are invincible while charging (doesn't include self-damage like Blood Donation machines), The dash deals x4 your current tear damage + 8, Doesn't have to be in a straight line, you can hold another button to curve it, Has a 3 second cooldown before it can be used again, While not moving your speed rapidly increases up to a bonus of +0.5, While you have this +0.5 bonus, moving will cause Isaac to fart around the room, spawning poison gas clouds, The farts stop spawning once you reach your regular movement speed, Poison deals damage equal to half your tears per tick, Isaac is immune to Poison from enemies, such as Gasbag, Gives you a wide circle halo which grants 7 orbital tears upon entering a new room, The tears orbit for 13 seconds before dropping off, Has a chance to absorb any enemy tears and add them to the orbiting tears. Half hearts heal a whole heart and full hearts heal 2 red hearts, UNLOCK: Unlock this item by beating Boss Rush with Maggy, * item room, treasure room, item room pool, the lost item pool, pink, purple, candy, Each time you enter a new room, damage is negated for the first time you get hit, Can be used to go in and out of a Curse Room without taking damage. PC 9SS3 3YXY (Second floor treasure room) (+ Technology 2 on third floor), PC GXSE V7P4 (Treasure Room adjacent to spawn), PC EZTZ CL68 (Treasure Room adjacent to spawn), PC RR0G KKQJ (Treasure Room adjacent to spawn), PC 6FDS 6FWF (Treasure Room adjacent to spawn), PC PCM8 R3H4 (Treasure Room adjacent to spawn), PS4 GXA1 L6XC (Treasure Room adjacent to spawn), PS4 27T2 26G0 (First floor Treasure Room), 3DS 11DA E0JZ (Treasure Room adjacent to spawn), Switch AL2T Q6NC (First Golden Treasure Room), Achievements Binding of Isaac: Rebirth Wiki is a FANDOM Games Community. The observational . Charge time increased to 4 (from 2), UNLOCK: Unlock this item by dying 100 times, * item room, treasure room, item room pool, grey, gray, Holding the active item button will deplete the charge bar. ?, Satan and The Lamb as Tainted Isaac, Every time you enter a brand new room, you have a chance to get a random one-time use Dice (e.g. Even if Isaac have not finished charging Brimstone when he'll pass through a door, it is always fully charged once a new room is entered if the fire button is still being held. Collection Grid Brimstone: Brimstone has priority. Poison, Homing, Prize Bombs), In Antibirth this was called Enigma Bombs, Spawns a red worm familiar that chases enemies nearby around the room and deals 2 contact damage per tick. Poops spawned by Tainted ??? All dead names. Challenges After a few seconds a huge missile hits the target and deals 20x your tear damage to anything nearby, Essentially a one-time use of the Epic Fetus item, * item room, treasure room, item room pool, grey, gray, robot, Isaac's tears now have a piercing effect which allows them to travel through enemies instead of breaking on hit, * item room, treasure room, item room pool, arrow, penetrative, penetrating shots, grey, gray, It rerolls enemies and pickups it comes into contact with, then despawns. Pickups Tears are fired in an arc. Sad Bombs: Bob's Brain will fire tears upon exploding. as Jacob & Esau, This item has a different effect for each character. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row), I'm Drowsy - Slows all enemies for the rest of the current room, I'm excited!!! These stack with multiple secret rooms - The first one gives +1.00 Tears Up, then all future ones give +0.5. Couldn't bomb into it or anything, no clue what it is. Brimstone is a passive item. Lasers sound deeper and bassier. purple, An orbiting fly which deals 2 contact damage per tick to enemies, * item room, treasure room, item room pool, blue, Has a chance to drop from the Super Gluttony miniboss fight, Item Pool: Item Room, Super Gluttony Miniboss, * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub, Allows Isaac to fly while the Pony is held, Sets your speed stat to 1.5 if it isn't already that high, When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits, Drops from the Headless Horseman boss fight, REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). . Changed to 2 room recharge, * golden chest pool, gold chest pool, item room, treasure room, item room pool, bob sloth, A clot that blocks blood flow to the heart can cause a heart attack. While at full red health you also shoot a projectile across the room with each swing, dealing your current Damage + 2 (similar to the Master Sword in Zelda), UNLOCK: Unlock this item by defeating challenge #39 (Isaac's Awakening), While held, a red outline of a door will appear on certain walls. Each time you clear a room there is a chance a Red Room will spawn at one of the walls. Those tears will cause the same effect if they happen to hit other enemies, Effects that replace your tears such as Brimstone simply have a chance to apply this effect, Any enemies that come within close range of Isaac will become feared, which causes them to flee, When used, this item takes away 5 of your coins and gives a +1.2 Damage Up that lasts for the current room, Can stack as many times as you want. Rebirth item concepts, including Monstro's Lung. If you have varicose veins, warning signs of a DVT include: A vein that bulges out and does not flatten when you lay flat or raise your leg. It also no longer prevents damage from self-harming mechanics e.g. This is a one-time use of the Red Key item. shop item pool, brown, x, cross, paper, Isaac has a random chance to fire another tear out the back of his head, The chance to fire the second tear can improve based on your luck stat and will always activate at +5 Luck, At +0 luck theres a ~50% chance for this effect to activate, Synergizes very well with a lot of items. Haemolacria tear appearance with Dr. Fetus. Poison deals 5 damage initially and then 3.5, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Isaac, REPENTANCE - GB Bug is now a thrown projectile, activated by double tapping an attack button. Hook Worm, Wiggle Worm etc. Curse Rooms and Blood Donation Machines don't trigger this effect, Items with a price will spawn the extra item free of charge (i.e. sack, pouch, blue, purple, Tears gain a damage up and increase in size based on the distance they travel, The length of a normal room roughly gives +6 damage, but this can be higher with double rooms or Tiny Planet, This item synergises with beam items such as Brimstone and Tech, allowing them to do more damage the further away the enemy is, When used, removes one heart container and gives you 3 soul hearts, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Harn 1.00 ms de dao y tendrn 5.25 ms de rango que las lgrimas normales disparadas por el ojo derecho. you could find a caves boss in the basement. Brimstone is actually one of the best items, combine that with brimsnapping and it being very accesible due to being a common item in Devil Rooms and you get yourself a loyal safety net. Attempting to fire the beam before it is fully charged will cancel the charge. ?, Satan and The Lamb as Tainted Samson, When taking damage you have a chance to explode and deal 185 damage to all enemies around you (Same damage as a Mr. Mega bomb), UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson, Familiars follow Isaac's exact movements, (similar to how Jacob & Esau work) instead of following loosely like they usually do, Holding the drop button (Ctrl on Steam version) causes them to stop moving, Doesn't affect some familiars with specific movement patterns, e.g. Chocolate Milk - Charge time is reduced and the eye starts flashing after 2 seconds of full chocolate milk charge, giving larger tears. Pressing the bomb button will put the next poop into the 'Hold' jar. item room pool, question mark book, white, When used, spawns 4-8 friendly blue spiders on the floor, REPENTANCE - Used to give 1-4 spiders per use, * item room, treasure room, item room poolgrey, gray, Allows you to fire a red flame infront of you, similar to the Blue Candle item, however the flame will stay 10 seconds, Each flame deals 125 total damage before it disappears, The flame will shrink in size when deals damage to something and eventually disappear, REPENTANCE - Red Candle flames now time out after ten seconds and automatically extinguish. Completion Marks When you take damage and the cannon breaks, you take an additional 2 full hearts of damage and gain the Anemic effect for the room. Isaac's Heart Loki's Horns Bouncy Tears Homing Tears Tammy's Head Tiny Planet Tough Love The Wiz Incubus Epiphora Dead Eye Pupula Duplex Tractor Beam Evil Eye Dead Tooth Eye of Greed Glaucoma Eye of Belial Ghost Pepper Large Zit Rag Mega's Orbitals aren't affected by her shots. It leaps at enemies, dealing contact damage and firing quad shots at them for the rest of the room. The laser deals damage equal to Isaac's damage and deals damage each tick. This includes damage you deal, and environmental damage they take e.g. Each of them deal double your tear damage, similar to how standard blue flies work, War (Red) - Explodes when touching the enemy. Items Each poop has random effects like Butt Bombs, Fire Poops etc, Tainted Blue Baby starts with this item, and is the only one who can use it, Spawns 3 random coins and a key when picked up, Buying items from the shop gives you random stat upgrades. The special shop contains various consumables and items at a higher price from the Devil/Angel room, Boss room and Secret room pools. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies), Enemies touching the cube while it's not moving or moving slowly will become slowed for a few seconds, and take a small amount of damage, Cube Baby and enemies frozen will block enemy shots, Cube Baby can be launched across the room if you have a melee weapon, Enemies that die now spawn a red ghost, that floats in place of where the enemy died, Activating the item causes all red ghosts in the room to explode, dealing damage to any enemies near them, The explosion doesn't deal damage to Isaac, Damage dealt by each ghost is 3 + 0.04x the HP of the enemy it spawned from, Larger enemies such as minibosses will spawn a larger red ghost that causes 3 explosions, The red ghosts can be moved around slightly by firing tears through them, Using the item will instantly kill any enemy or boss that has the 'ghost' tag and is at 50% or less HP. Soy Milk) can lead to interesting synergies, * astrology, astronomy, item room, treasure room, item room pool, ohm, blue, glow, Isaac's tears turn bright green and always apply a poison effect to enemies which deals a total of double your tear damage, This is essentially a superior version of The Common Cold item, * astrology, astronomy, item room, treasure room, item room pool, m, tail, blue, glow, Tears do not travel through rocks with this item, *astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, Item Icon His family was his most cherished possession and was his . Item Pool: Item Room, Demon Beggar, Lust Miniboss, * demon beggar pool, demon judgement pool, devil beggar pool, item room, treasure room, item room pool, syringe, needle, injection, the lost item pool, red, Item Pool: Item Room, Boss Room, Demon Beggar, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, green, Has a chance to drop from the Gluttony miniboss fight, * boss room pool, boss room item, item room, treasure room, item room pool, red heart, ballchinnian, ball sack, full heal, gluttony, the lost item pool, * secret room pool, the lost item pool, brown, poop, turd, * secret room pool, silver, grey, gray, skull, Can drop from an exploding slot machine while playing it, * slot machine, arcade machine, money, bill, cash, green, * boss rush pool, boss rush room, item room, treasure room, item room pool, grey, gray, x10, UNLOCK: Unlock this item by beating Mom's Heart 3 times, * secret room pool, the lost item pool, brown, noose, hang, Shows most icons on the map (Shops, Item Rooms, Boss Rooms etc. And items at a higher price from the Devil/Angel room, boss room and secret room pools could... 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